Coagulation Disorders in Pancreatic Cancer

A Female Presenting with Trousseau Syndrome in End-stage Pancreatic Cancer: A Case Report

Volume 2 • Issue 1 • 2013 Introduction A case of thrombosis associated with a malignant tumor was first reported by Trousseau in 1865 [1], which supposedly resulted from chronic disseminated intravenous coagulation. Later, malignant tumors were found to occasionally accompany arterial or venous thrombosis, pulmonary embolisms, or non-infectious endocarditis [2,3]. Trousseau syndrome is associat...

Pancreatic Metastasis of Alveolar Rhabdomyosarcoma Presenting as Acute Pancreatitis

Association between alcohol consumption and pancreatic cancer: a systematic review of cohort studies

Background: Among all types of cancers, pancreatic cancer has poor prognosis with 5-year survival below 10%. In theory, alcohol intake may be a modifiable risk factor for pancreatic cancer due to its role in multiple carcinogenic and metabolic signaling pathways. In addition, alcohol consumption may lead to chronic pancreatitis which is underlying cause of pancreatic cancer. However, little is ...

Tumour imaging by the detection of fibrin clots in tumour stroma using an anti-fibrin Fab fragment

The diagnosis of early and aggressive types of cancer is important for providing effective cancer therapy. Cancer-induced fibrin clots exist only within lesions. Previously, we developed a monoclonal antibody (clone 102-10) that recognizes insoluble fibrin but not fibrinogen or soluble fibrin and confirmed that fibrin clots form continuously in various cancers. Here, we describe the development...

Atypical presentation of disseminated intravascular coagulation with synchronous peripheral venous thromboembolism and arterial gangrene in a pancreatic cancer patient: a case report.

CONTEXT Cancer is a prothrombotic state and anticancer therapies are often complicated by vascular events. The risk of developing thromboembolic events is substantially increased in patients with pancreatic cancer. One possible presentation of vascular events in pancreatic cancer is disseminated intravascular coagulation (DIC). CASE REPORT In our case a patient with a diagnosis of pancreatic ...